Differential packaging of inflammatory cytokines/ chemokines and oxidative stress modulators in U937 and U1 macrophages-derived extracellular vesicles upon exposure to tobacco constituents.
Smoking, which is highly prevalent in HIV-infected populations, has been shown to exacerbate HIV replication, in part via the cytochrome P450 (CYP)-induced oxidative stress pathway.Recently, we have shown that extracellular vesicles (EVs), derived from HERBATINT FF4 tobacco- and/or HIV-exposed macrophages, alter HIV replication in macrophages by ce